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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG3
All Species:
13.94
Human Site:
T725
Identified Species:
25.56
UniProt:
P49916
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49916
NP_002302.2
1009
112907
T725
P
G
S
Q
K
W
C
T
V
T
K
C
A
G
G
Chimpanzee
Pan troglodytes
XP_511409
922
102716
T650
A
G
G
H
D
D
A
T
L
A
R
L
Q
K
E
Rhesus Macaque
Macaca mulatta
XP_001113780
1009
112805
T725
P
G
S
Q
K
W
C
T
V
T
K
C
A
G
G
Dog
Lupus familis
XP_548265
991
110592
M708
G
Q
G
S
K
G
G
M
M
S
I
F
L
M
G
Cat
Felis silvestris
Mouse
Mus musculus
P97386
1015
113000
T730
P
D
S
Q
K
W
C
T
V
T
K
C
A
G
G
Rat
Rattus norvegicus
NP_001012011
943
105425
P670
D
V
K
G
T
Y
E
P
G
K
R
H
W
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006215
902
101303
T630
L
M
G
C
Y
D
P
T
S
E
K
W
C
T
V
Frog
Xenopus laevis
NP_001082183
988
110688
T687
P
E
G
Q
L
W
C
T
V
T
K
C
S
S
G
Zebra Danio
Brachydanio rerio
NP_001025345
752
84159
K480
E
V
L
L
I
D
T
K
T
S
K
P
L
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650187
806
90830
W534
D
A
N
A
I
P
S
W
L
L
C
S
K
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27474
773
86292
C501
Y
G
G
Y
L
L
G
C
Y
N
P
T
T
E
E
Sea Urchin
Strong. purpuratus
XP_786357
875
97201
A603
Y
L
K
E
G
S
M
A
D
S
A
D
L
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
I483
W
D
K
D
Q
G
K
I
L
P
F
Q
V
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
97.7
89.4
N.A.
87.3
82.4
N.A.
N.A.
71.3
68.2
55.7
N.A.
34.9
N.A.
23.3
48.4
Protein Similarity:
100
91.1
98.8
92.2
N.A.
91.3
86.4
N.A.
N.A.
78.9
79.6
64.9
N.A.
48.1
N.A.
39.3
62.9
P-Site Identity:
100
13.3
100
13.3
N.A.
93.3
0
N.A.
N.A.
13.3
66.6
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
26.6
100
26.6
N.A.
93.3
13.3
N.A.
N.A.
13.3
73.3
13.3
N.A.
13.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
8
8
0
8
8
0
24
0
0
% A
% Cys:
0
0
0
8
0
0
31
8
0
0
8
31
8
0
0
% C
% Asp:
16
16
0
8
8
24
0
0
8
0
0
8
0
0
0
% D
% Glu:
8
8
0
8
0
0
8
0
0
8
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% F
% Gly:
8
31
39
8
8
16
16
0
8
0
0
0
0
24
39
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
16
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
24
0
31
0
8
8
0
8
47
0
8
8
8
% K
% Leu:
8
8
8
8
16
8
0
0
24
8
0
8
24
24
8
% L
% Met:
0
8
0
0
0
0
8
8
8
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
31
0
0
0
0
8
8
8
0
8
8
8
0
8
0
% P
% Gln:
0
8
0
31
8
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
0
24
8
0
8
8
0
8
24
0
8
8
16
8
% S
% Thr:
0
0
0
0
8
0
8
47
8
31
0
8
8
8
0
% T
% Val:
0
16
0
0
0
0
0
0
31
0
0
0
8
0
16
% V
% Trp:
8
0
0
0
0
31
0
8
0
0
0
8
8
0
0
% W
% Tyr:
16
0
0
8
8
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _